In order to strengthen your profile so to have better opportunities in your career, i. e, for jobs or for higher studies you need to have good publications under your belt. The only program since 2010 which is fulfilling this need is the Research Project Training Program of BDG LifeSciences which is of novel research projects on the latest technologies of Bioinformatics.
In this program, we implement the current research trend and apply unique ways of teaching plus practical application so to make you learn in the best possible way. As it is done online hence participants have the freedom of choosing the time of training sessions according to their choice and also save a huge amount of money in travel, accommodation, food, etc., As of now we have completed more than 60 research projects and all of them published at International level. This research project can be done as a Major and/or thesis project for the final year or if someone wants to strengthen their profile. You can view all the completed projects here. To view the video feedback of our previous events kindly visit our YouTube Channel To view, the teams for current projects click here
CURRENT RESEARCH PROJECT
Our research project training program is of novel research projects on the latest technologies of Bioinformatics. In this program, we implement the current research trend and apply unique ways of teaching plus practical application so to make you learn in the best possible way. As it is done online hence participants have the freedom of choosing the time of training sessions according to their choice and also save a huge amount of money in travel, accommodation, food, etc., As of now we have completed more than 75 research projects and all of them published at International level. This research project can be done as a Major and/or thesis project for the final year or if someone wants to strengthen their profile so as to have better opportunities in their career, i. e, for jobs or for higher studies. Applications are invited for ONLY 1 SEAT in our 87 novel research project entitled "Decoding Pan-Cancer Pathogenesis: A Multi-Layered Analysis of Prognostic mRNAs, miRNAs, lncRNAs via Co-Expression Networks and PPINs"
FEE- In India Online: 46999 INR, Foreign Online: $ 899 USD
IF YOU WANT TO PAY DIRECTLY INTO THE BANK ACCOUNT THEN EMAIL ON research@bdglifesciences.com
LAST DATE OF REGISTRATION IS 31 OCTOBER 2024 AND THE PROJECT WILL START AFTER REGISTRATION
SUMMARY OF THE PROPOSED RESEARCH WORK:
This project aims to elucidate key prognostic mRNAs, miRNAs, and lncRNAs that are commonly implicated in pan-cancer mechanisms. The research will begin with the retrieval and analysis of RNA-Seq datasets relevant to pan-cancer, followed by the identification of hub genes through the establishment of co-expression networks and the application of critical network topology measures. Subsequently, a Protein-Protein Interaction Network (PPIN) will be constructed to pinpoint hub elements, leading to the identification of a robust prognostic signature. Pathway and Gene Ontology (GO) enrichment analyses will be conducted to uncover the associated signaling pathways. Furthermore, feed-forward loop (FFL) analysis will be employed to identify significant miRNAs, transcription factors (TFs), and lncRNAs related to prognostic genes, followed by an investigation of mutational profiles and tumor infiltration patterns.
DETAILED RESEARCH PLAN: MATERIAL AND METHODS
DURATION- 2-3 Months- training sessions will be conducted online on ZOOM/GOOGLE MEET/MICROSOFT TEAMS
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EXPECTED OUTCOMES:
Novel prognostic genes along with other regulatory elements responsible for the pathogenesis of pan-cancer will be identified via robust multiomics and network-based approach. The hub module genes will be subjected to prognostic, PPIN. enrichment, FFL, mutational and tumor infiltration analyses.
BASIC SKILL REQUIREMENT
TOPICS
TOOLS & SOFTWARE
ELIGIBILITY: Anyone who is a UNDERGRADUATE/GRADUATE or HIGHER DEGREE is the minimum requirement to register for this project. This project is strictly not for HIGH SCHOOL (Class 9 & 10) / COLLEGE (Class 11 & 12) students. For them we have other projects which can be presented in Science Fair.
WHAT YOU GET
T & C
TEAM FOR CURRENT/ONGOING RESEARCH PROJECTS
87. Decoding Pan-Cancer Pathogenesis: A Multi-Layered Analysis of Prognostic mRNAs, miRNAs, lncRNAs via Co-Expression Networks and PPINs
86. Unveiling Autoimmune Genes and Regulatory Elements in Head and Neck Squamous Cell Carcinoma through Advanced Machine Learning and Network-Based Analysis
85. Molecular Modeling study of derivatives of Leaf Extracts of medicinal plant Solanum torvum and Serine/Threonine Kinase from Mycobacterium Tuberculosis
84. Targeting Tumor Progression: Identifying Differentially Expressed Genes and Pathways in Pancreatic Ductal Adenocarcinoma using RNAseq
83. Next Generation Sequencing | Unraveling the Cancer Code: Gene Expression Profiling with RNAseq
82. NGS Data Analysis | Prediction of Multiple Myeloma Using RNASeq Data
81. NGS Data Analysis of Cancer Tissues | A Cancer Biology Study
79. Molecular Modeling study of Cyclophilin A and derivatives of Ganoderiol F (26,27-Dihydroxylanosta-7,9(11),24-trien-3-one): Design of novel inhibitors for CyclophilinA
78. Molecular Modeling study of derivates of Ethyl 2-[(4-chlorophenyl)carbamoylamino]-5-methyl-4-phenylthiophene-3-carboxylate and α-D-glucose-1-phosphate thymidylyltransferase (Mycobacterium-RmlA) | Discovery of new drugs for multidrug-resistant (MDR)Mtb
76. Molecular Modelling study of p53-MDM2 and derivatives of Ganoderiol F | Discovery of new Anti-CANCER Drugs by Molecular Docking & MD Simulations Approach
75. NGS Data Analysis on Alzheimer's
74. NGS Data Analysis on Cancer Biology | Analyzing cancer tissues
73. Inhibitory study of Focal Adhesion Kinase (FAK): A Virtual screening, Molecular Docking & ADMET study for combating cancer
72. Virtual Screening and Molecular Docking study of derivatives of chromen-2-one as selective Estrogen Receptor beta Agonists (SERBAs): Molecular Modeling study of Benign Prostatic Hyperplasia
71. Molecular Modeling Study of extracts of medicinal plants as potential anti-tubercular agents
70. Virtual screening & Molecular Docking of DOT1L & derivatives of Pinometostat | Molecular Modeling study of Therapeutic Target in Mixed-lineage Leukemia (MLL)
69. Targeting the Wnt/β-catenin signaling pathway in cancer by molecular modeling study of Ganoderiol F and Beta- Catenin
68. Biomarker discovery based on omics technology
67. Study of SARS-CoV-2 main protease (Mpro) and derivatives of Norterihanin to investigate potential inhibitors using Virtual Screening & Molecular Docking
66. Molecular Modelling study of SARS-CoV-2 spike protein of COVID-19 with derivatives of Saikosaponins | Examining the anticoronaviral activity of saikosaponins (A, B2, C and D)
65. Molecular Modeling study of Southeast Asian Medicinal Plant Aglaia erythrosperma and α-D-glucose-1-phosphate thymidylyltransferase (Mycobacterium-RmlA) | Discovery of new drugs for multidrug-resistant (MDR) Mtb
64.Molecular Modeling study of Cyclophilin A and derivatives of 1,8-Diamino-2,4,5,7-tetrachloroanthraquinone: Design of novel inhibitors for Cyclophilin A
63. Molecular Modelling study of Catalytic domain of protein kinase PknB from Mycobacterium tuberculosis | Discovery of new Anti-Tubercular Drugs
62. Molecular Modelling study of p53-MDM2 | Discovery of new Anti-CANCER Drugs by Molecular Docking & MD Simulations Approach
61. Molecular modeling of sphingosine 1-phosphate receptor 1(S1P1) as target for multiple sclerosis | A Virtual screening, Molecular docking & ADMET study
60. Inhibitory study of α-D-glucose-1-phosphate thymidylyltransferase (Mycobacterium-RmlA) | Discovery of new drugs for multidrug-resistant (MDR) Mtb
59. Molecular modeling study of derivatives of dutasteride and Human Steroid 5β-Reductase (AKR1D1) | Discovery of new drugs for prostate cancer
57. Molecular modeling study of α-glucosidase Inhibitors (AGIs) | Discovery of new anti-diabetic drugs by controlling postprandial hyperglycemia
56. Discovery of new ligands for PPAR Gamma responsible for Diabetes Type 2: A Virtual Screening, Docking & ADMET Study.
53. Molecular Modelling study of phytoconstituents from medicinal plants of India | Discovery of natural anti-tubercular agents
49. Molecular Modeling study of Zika Virus | Virtual Screening, Protein Modeling, Docking, ADMET and MD Simulations Study
39. Study of derivatives of Chalcones as new Tyrosinase inhibitors: A Molecular Docking, ADME & Tox Study
34. Study of extracts of Veratrum Dahuricum as potential Anti-tumor molecules: Molecular Docking & Modeling study with Farnesyl Pyrophosphate Synthase (FFPS)